On my direct drive Voron I could make it through retraction tower test prints fine with TPU, but it would always jam with retraction enabled on longer prints with my usual 0.3mm. Pulling apart the extruder would always reveal some TPU had gotten wrapped around the drive gear. Rather than try tuning until the failure went away, I just went with 0 lol.
TIL there’s a slicer called Lychee Slicer.
Sounds like a hot mess. Are you looking for a alternative? If yes, provide info but my off the cuff recommendation for a FDM printer is Orca Slicer.