I also love Yotsubato! :) sometimes it blows my mind that’s it’s the same author as Azumanga Daioh
My #1 favorite is Nausicaa of the Valley of the Wind, it’s several times longer and more complex than the movie.
10/10: Nausicaa, Girls’ Last Tour
Almost 10/10: Himegoto: Juukyuusai no Seifuku
9/10: B-gata H-kei, Genjitsu Touhi shitetara Boroboro ni Natta Hanashi (the Nagata Kabi alcoholism memoir), Mata Onaji Yume wo Miteita
Other favorites: Kobayashi’s Dragon Maid, Nichijou, Onimai, Melancholia & Nickelodeon, March comes in like a lion, Onanie Master Kurosawa, Gakkougurashi. Maybe parts 6 and 7 of Jojo’s
Cancer treatment also has had lots of improvements but they aren’t newsworthy if they’re not the Cure to Cancer™️