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Cake day: June 27th, 2023

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  • Sorry, deleted my comment because I realized the bands I was thinking of weren’t really punk necessarily, though they are counterculture. I really like Speedy Ortiz–they’ve toured with some big names like Liz Phair, and recently did a Tiny Desk concert. A few months ago i saw them live and a band called Suzie True opened, which is a little introspective about problems still but I think has a ton of potential to write some banger callout /protest songs and I’ve really enjoy listening to them.




  • I for sure think that the DNC aren’t to blame in the same way that a firefighter who uses a garden hose to try to put out a burning house isn’t responsible for the smoking ruins when there are other people throwing molotovs through the windows, slashing the tires of the firetrucks, and getting the neighbors to throw bricks at the firefighters.

    That being said, if my house was on fire and it was clear that I couldn’t get the active vandals to stop despite them burning themselves in the process, I think it’s justified to work on replacing or training the firefighters to be more competent and/or rutheless with dealing with the threat.




  • Sorry, I meant she should have been Bernie-style grandstanding about it and hammering it home and making it a core part of her campaign more than it not being in her plans at all. I feel like she started with that kind of message and was doing well and ended with the Cheneys like me and ill put a Republican in my cabinet and lost




  • niucllos@lemm.eetoLefty Memes@lemmy.dbzer0.comWhat year is it?
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    6 days ago

    One example does not a rule make, and in the US electoral system money (and the party affiliations that bring it) speaks loudest of all. Maybe going further left wouldn’t work, but going further right certainly hasn’t. When Harris first emerged as the candidate she had such a swell of support, as she moved further right she lost it.


  • niucllos@lemm.eetoScience Memes@mander.xyz...
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    19 days ago

    Sure, there will be examples of problems in any field that has hundreds of thousands to millions of humans working in it. That doesn’t mean there’s a broad crisis, and it doesn’t mean that most research is faked or fallible. In your 2004 example, all of the data wasn’t faked, some images for publication were doctored. There’s been potential links between alzheimer’s and aBeta amyloids since at least 1991 (1), long before this paper that posited a specific aB variant as a causal target. Additionally, other Alzheimer’s causes and treatments are also under investigation, including gut microbiome studies since at leasg 2017 (2). Finally, drugs targeting aB proteins to remove brain plaques work in preclinical trials, indicating that the 2004 paper was at least on the right track even if they cheated to get their paper published. This showcases science working well: bad-faith actors behaved unethically, but the core parts of their work were replicated and found to be effective, so some groups followed that to clinical trials which are still ongoing, and others followed other leads for a more holistic understanding of the disease.

    Also, I’d very much argue that human neurological diseases are both bleeding edge and niche, which inherently means that recognizing problems in studies will take more time than something that is cheaper or faster to test and validate, but problems will eventually be recognized as this one was.

    1. Cras P, Kawai M, Lowery D, Gonzalez-DeWhitt P, Greenberg B, Perry G. Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein. Proc Natl Acad Sci USA. 1991;88:7552–6.
    2. Cattaneo, A. et al. Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly. Neurobiol. Aging 49, 60–68 (2017).

  • niucllos@lemm.eetoScience Memes@mander.xyz...
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    20 days ago

    I wouldn’t call it a broad crisis, and it isn’t universal. More theoretical sciences or social sciences are more prone to it because the experiments are more expensive and you can’t really control the environment the way you can with e.g. mice or specific chemicals. But most biology, chemistry, etc that isn’t bleeding edge or incredibly niche will be validated dozens to hundreds of times as people build on the work and true retractions are rare



  • My aunt is a big gardener in 7a (piedmont NC) and has overwintered jalapenos a few times and declared it not worth it for her, apparently the yields aren’t much/any bigger than new seedlings and it’s a nontrivial amount of work and space to keep them overwintered. If you try again and have different results I’d love to hear about it!